6533b85bfe1ef96bd12bac1f

RESEARCH PRODUCT

A dammarane-type saponin from the roots of Ampelozizyphus amazonicus.

Maria G.l. BrandãoMarco Antônio TeixeiraHans-ulrich WagnerHans-ulrich WagnerMarie Aleth Lacaille-duboisMarie-aleth Lacaille-dubois

subject

chemistry.chemical_classificationAmpelozizyphusMagnetic Resonance SpectroscopyPlants MedicinalbiologyStereochemistryDammaraneMolecular Sequence DataSaponinPlant ScienceGeneral MedicineHorticultureSaponinsbiology.organism_classificationBiochemistryTriterpeneschemistry.chemical_compoundTriterpenechemistryCarbohydrate SequenceRhamnaceaeMolecular BiologyTwo-dimensional nuclear magnetic resonance spectroscopyTriterpenoid saponin

description

A new C31 dammarane-type triterpenoid saponin has been isolated from the roots of Ampelozizyphus amazonicus. Its structure was elucidated to be ampelozigenin-15 alpha-O-acetyl- 3-O-alpha-L-rhamnopyranosyl-(1--2)-beta-D-glucopyranoside by 1D and 2D NMR spectroscopic methods, and by chemical transformations. Ampelozigenin is a novel triterpene, (20R,22R)-16 beta,22:16 alpha, 30-diepoxydammar-24(24')- methylene-3 beta, 15 alpha, 20-triol.

10.1016/s0031-9422(00)90728-3https://pubmed.ncbi.nlm.nih.gov/7764239