6533b85bfe1ef96bd12bb566

RESEARCH PRODUCT

Development of trackable metal-based drugs: new generation of therapeutic agents

Christine GozeEwen BodioPierre-emmanuel DoulainBenoît BertrandBenoît Bertrand

subject

Diagnostic ImagingExploitTheranostic NanomedicineComputer scienceNanotechnologyphosphine-porphyrinpotential anticancer agents[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistry01 natural sciencesin-vivo[ CHIM ] Chemical SciencesTheranostic NanomedicineInorganic Chemistrytheranostic agentsplatinum(ii) complexesorganometallic compoundsAnimals[CHIM]Chemical Sciences010405 organic chemistry[ CHIM.INOR ] Chemical Sciences/Inorganic chemistry0104 chemical sciences3. Good healthcancer-cellsRisk analysis (engineering)photodynamic therapycytotoxic propertiesDrug Designheterocyclic carbene complexes

description

International audience; In medicinal chemistry, the aim is not only to conceive ever more efficient molecules, but also to understand their mechanism of action. In very recent years, a new promising strategy was developed to tackle this issue: the conception of trackable therapeutic agents. Metal-based drugs are ideal to exploit this expanding area of research.

https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01402883