6533b85bfe1ef96bd12bbddb
RESEARCH PRODUCT
Covariate-constrained Randomization Routine for Achieving Baseline Balance in Cluster-randomized Trials
Sabine GabryschEva LorenzEva Lorenzsubject
Restricted randomizationmedicine.medical_specialtyRandomizationRandomization ProcedureComputer sciencelaw.invention03 medical and health sciences0302 clinical medicineMathematics (miscellaneous)Physical medicine and rehabilitationRandomized controlled triallawStatisticsCovariatemedicine030212 general & internal medicineBaseline (configuration management)Trial Arms030217 neurology & neurosurgeryBalance (ability)description
In cluster-randomized trials, groups or clusters of individuals, rather than individuals themselves, are randomly allocated to intervention or control. In this article, we describe a new command, ccrand, that implements a covariate-constrained randomization procedure for cluster-randomized trials. It can ensure balance of one or more baseline covariates between trial arms by restriction to allocations that meet specified balance criteria. We provide a brief overview of the theoretical background, describe ccrand and its options, and illustrate it using an example.
year | journal | country | edition | language |
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2017-06-01 | The Stata Journal: Promoting communications on statistics and Stata |