6533b85bfe1ef96bd12bbe48

RESEARCH PRODUCT

Relationship Between Size and Oxygenation Status of Malignant Tumors

J. OtteJ. OtteR. ManzR. ManzPeter VaupelPeter VaupelGerhard ThewsGerhard Thews

subject

Pathologymedicine.medical_specialtybusiness.industryWeight classTumor microcirculationmedicineOxygenationTumor vascularizationbusinessMalignant Growth

description

During advanced phases of malignant growth, there are typical changes in the microvasculature pattern within the tissue of many solid tumors. Partly due to these peculiarities of tumor vascularization, a series of characteristic variations of tumor microcirculation occurs (for a review see 1). These alterations lead not only to marked restrictions and inhomogeneities of both convective and diffusive transport but also to an impairment of the efficiency of antitumor therapies.

https://doi.org/10.1007/978-1-4684-7790-0_34