6533b85cfe1ef96bd12bc5dd

RESEARCH PRODUCT

Ecologie évolutive de la malaria aviaire : effets des caractéristiques de l'hôte et de l'environnement

Coraline Bichet

subject

Malaria aviaire[SDV.SA] Life Sciences [q-bio]/Agricultural sciencesMate choiceCanari domestique[SDV.BA] Life Sciences [q-bio]/Animal biologyChoix de partenaireDomestic canariesMajor histocompatibility complexLife history traitsEnvironment[ SDV.BA ] Life Sciences [q-bio]/Animal biologyTraits d’histoire de vieEnvironnementImmune systemSystème immunitaireAvian malariaComplexe majeur d’histocompatibilitéHouse sparrowMoineau domestique[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciences

description

Host-parasite interactions are one of the main topics in evolutionary sciences. This complex coevolution depends on several trade-offs and can be influenced by environmental factors. Here, we propose to study host-parasite interactions with a multi-level approach, using experimental and natural population studies, focusing on avian malaria parasites. First, we studied the effect of host characteristics, and more precisely the immune system. The immune system confers benefits in terms of protection against the parasite, but can also generated immunopathological costs. Life history traits, like age or social status, appear to modify parasitemia but not prevalence. In a second part, we evaluated the effect of environmental factors on host-parasite interactions. We found that temperature and heavy metal contamination had an effect on population prevalence, but not on host parasitemia. We also showed the direct parasite influence on host population genetic structure, and more precisely on MHC genes.

https://tel.archives-ouvertes.fr/tel-00907956/document