6533b85cfe1ef96bd12bcb5a
RESEARCH PRODUCT
Characterization ofBacillus thuringiensisisolated from infections in burn wounds
Per Hyldebrink DamgaardMaria Valeria TorregrossaJosé BrescianiJørgen EilenbergPer E GranumL. Valentinosubject
Microbiology (medical)Bacterial ToxinsImmunologyBacillus thuringiensisBacillus cereusAedes aegyptiEnterotoxinMicrobiologyMicrobiologyHemolysin ProteinsBacterial ProteinsAedesBacillus thuringiensisChlorocebus aethiopsAnimalsHumansImmunology and AllergyVero CellsPieris brassicaeBacillus thuringiensis Toxinsbiologybacillus thurigiensisinfectionsfungiGeneral Medicinebiology.organism_classificationBacillalesVirologyEndotoxinsInfectious DiseasesWound InfectionVero cellBurnsButterfliesBacteriadescription
Four strains of Bacillus thuringiensis were isolated from infections in burn wounds and from water used in the treatment of burn wounds. The strains produced large parasporal inclusion bodies composed of 141, 83, and 81 kDa protoxins. The four strains were tested for insecticidal activity against larvae of Pieris brassicae and Aedes aegypti but showed no activity; Vero cell assays for the production of enterotoxins were also negative. Attempts to classify the strains according to flagellar H-serotype showed them all to be non-flagellated. Apart from two occupational health accidents that occurred during the handling of highly concentrated B. thuringiensis fluids, this is the first report of B. thuringiensis causing non-gastrointestinal clinical infection in immunosuppressed patients.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-05-01 | FEMS Immunology & Medical Microbiology |