6533b85cfe1ef96bd12bd2b0
RESEARCH PRODUCT
Total synthesis of the monoterpenes (−)-mintlactone and (+)-isomintlactone
Miguel CardaJ. Alberto Marcosubject
chemistry.chemical_classificationBicyclic moleculeChemistryMonoterpeneOrganic ChemistryTotal synthesisRing (chemistry)BiochemistryIsomintlactoneDrug DiscoveryOrganic chemistryStereoselectivityMINTLACTONELactonedescription
Abstract The first total stereodirected synthesis of the monoterpenes (−)-mintlactone and (+)-isomintlactone from the same chiral starting product is described. A stereoselective, radical-mediated ring closure was the key step in both syntheses.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-01-01 | Tetrahedron |