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RESEARCH PRODUCT

Outpatient minor oral surgery in patients with hemophilia: A case series of 23 patients

Gabriela GuerreroAlejandra BaquesMarcelo O. MiniguttiEmilio Andrés RamosDiego CarusoMaximiliano DiamanteJosefina GutierrezLudmila Betsabé AntonelliJuan M. Muiño

subject

medicine.medical_specialtybusiness.industryOral surgeryCase Report030206 dentistry030204 cardiovascular system & hematology:CIENCIAS MÉDICAS [UNESCO]Surgery03 medical and health sciences0302 clinical medicineCoagulationHemostasisUNESCO::CIENCIAS MÉDICASAmbulatoryMedicineLocal anesthesiaIn patientOral SurgerybusinessGeneral DentistryCoagulation DisorderTranexamic acidmedicine.drug

description

Hemophilia is an inherited coagulation disorder characterized by deficiency of the coagulation factor VIII or IX. When the management of hemostasis is inadequate, these patients are at high risk of experiencing intra and postoperative bleedings after tooth extractions. Coagulation factor replacement therapy allows performing most surgical procedures safely, although the factor levels and length of treatment have not been clearly determined. In this study, we present our experience in a retrospective series of 112 ambulatory tooth extractions under local anesthesia in 23 patients with hemophilia using a coagulation factor replacement therapy in combination with tranexamic acid. The results obtained with this protocol were satisfactory and only one episode of mild postoperative bleeding occurred after seven days in a patient who did not have good treatment compliance. Key words:Hemophilia, factor replacement therapy, tooth extractions, postoperative complications.

https://doi.org/10.4317/jced.55506