6533b85dfe1ef96bd12be499

RESEARCH PRODUCT

OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS

Ivana PibiriAndrea PaceMarco TutoneLaura LentiniRaffaella MelfiAldo Di Leonardo

subject

oxadiazoles read through promoters TRIDs Cystic Fibrosis genetic diseases nonsense mutations premature termination codons drugs

description

Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.

yearjournalcountryeditionlanguage
2018-01-01
http://hdl.handle.net/10447/391635