6533b85dfe1ef96bd12be59a

RESEARCH PRODUCT

Development of a simulation chamber for the evaluation of dermal absorption of volatile organic compounds

Soraya Pontes-lópezFrancesc A. Esteve-turrillasJulia MorenoSergio Armenta

subject

Atmospheric Science010504 meteorology & atmospheric sciencesPolydimethylsiloxaneDiffusionAnalytical chemistryBTEX010501 environmental sciences01 natural sciencesPollutionEthylbenzeneToluenechemistry.chemical_compoundMembraneFlux (metallurgy)chemistryBenzeneWaste Management and Disposal0105 earth and related environmental sciences

description

Abstract An exposition chamber has been designed and developed for the production of contaminated atmospheres with fixed and known concentration of volatile organic compounds. The proposed chamber has been evaluated for the determination of in-vitro diffusion parameters, such as flux and lag time for benzene, toluene, ethylbenzene, and xylenes (BTEX). Polydimethylsiloxane (PDMS) and Strat-M® membranes were evaluated, including the effect of membrane thickness, from 0.5 to 3.0 mm, on the diffusion parameters. The obtained flux values and lag times, ranged from 0.2 to 1.5 μg cm−2 h−1 and from 10 to 130 min, respectively, for studies performed at a BTEX concentration of 51 μg L−1 in air. Different air concentration of BTEX were evaluated in the calibration chamber, indicating that flux increased proportionally to the BTEX concentration in air and the lag time decreased as the air concentration of BTEX increased.

yearjournalcountryeditionlanguage
2020-05-01Atmospheric Pollution Research
https://doi.org/10.1016/j.apr.2020.02.015