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RESEARCH PRODUCT
FIA-fluorimetric determination of adrenaline by oxidation with a solid-phase reactor of manganese dioxide incorporated in polyester resin beads
J. Martínez CalatayudAnatol Kojłosubject
Flow injection analysisChromatographyCalibration curveBiochemistry (medical)Clinical BiochemistryFluorescence spectrometrychemistry.chemical_elementManganesePharmaceutical formulationBiochemistryDosage formAnalytical ChemistrychemistryElectrochemistrySample preparationQuantitative analysis (chemistry)Spectroscopydescription
Abstract The FIA-spectrofluorimetric determination of adrenaline was carried out by reaction of the drug with manganese dioxide entrapped in a polymeric material in a solid-phase reactor; the oxidized drug was monitored fluorimetrically at 540 nm (Ioxg. 330.0 nm). The calibration graph for adrenaline was linear over the range 0.5 - 20 μg ml−1 with a relative standard deviation of 2.0% (at 5 ug ml−1) and the sample throughput of 65 h−1. The influence of foreign compounds was studied and the method was applied to the determination of adrenaline content in a pharmaceutical formulation . ∗Present address: Institut of Chemistry, Warsawa University, Bialystok Branch, Bialystok, Poland.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1995-01-01 | Analytical Letters |