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RESEARCH PRODUCT
Strecker reactions with hexacyanoferrates as non-toxic cyanide sources
Till OpatzCaroline Grundkesubject
010405 organic chemistryCyanidePotassiumStrecker amino acid synthesischemistry.chemical_element010402 general chemistry01 natural sciencesPollution0104 chemical scienceschemistry.chemical_compoundchemistryEnvironmental ChemistryOrganic chemistryFerrocyanidedescription
The Strecker reaction is the most widely applied three-component reaction. Although highly useful for the preparation of α-amino nitriles, α-amino acids, hydantoins and numerous related compounds, the need for the application of toxic sources of HCN limits its application in both academic and industrial settings. Here, we present a facile protocol for Strecker reactions using a mixture of potassium ferri- and ferrocyanides as a non-toxic substitute.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 | Green Chemistry |