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RESEARCH PRODUCT

Protonation of 3-aminopyrroles

Gaetano DattoloR. Alan JonesWerner HinzEnrico AielloAnna Maria AlmericoGirolamo Cirrincione

subject

ChemistryStereochemistryNuclear TheoryOrganic ChemistryProtonationNuclear magnetic resonance spectroscopyRing (chemistry)BiochemistryMedicinal chemistrychemistry.chemical_compoundDrug DiscoveryPhysics::Accelerator PhysicsChemical solutionNuclear ExperimentSpectroscopySpectral dataPyrrole

description

Abstract The protonation of 3-aminopyrroles has been investigated using H and 13C n.m.r. spectroscopy. The spectral data are compatible with predominant protonation of the amino group with no evidence for protonation of the pyrrole ring.

https://doi.org/10.1016/s0040-4020(01)87697-3