6533b85efe1ef96bd12bfe8f
RESEARCH PRODUCT
N-{4-[4-(4-Fluorophenyl)-1-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]-2-pyridyl}-2-methyl-3-phenylpropionamide
Stefan LauferDieter SchollmeyerKatharina Zieglersubject
CrystallographyGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsRing (chemistry)Organic PapersMedicinal chemistryCrystalchemistry.chemical_compoundchemistryQD901-999SulfanylAmidePyridineImidazoleGeneral Materials Sciencedescription
In the crystal structure of the title compound, C28H29FN4O2S, the imidazole ring makes dihedral angles of 11.85 (7), 73.33 (7) and 22.83 (8)° with the 4-fluorophenyl, pyridine and phenyl rings, respectively. The 4-fluorophenyl ring makes dihedral angles of 77.91 (7) and 26.93 (8)° with the pyridine and phenyl rings, respectively. The phenyl and pyridine rings are nearly perpendicular, making a dihedral angle of 86.47 (9)°. The crystal packing shows an intermolecular N—H...O hydrogen-bonding interaction between the N—H and carbonyl groups of the amide functions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-11-01 | Acta Crystallographica Section E Structure Reports Online |