Fludarabīna fosfāta injekciju piemaisījumu metodes izstrāde stabilitātes pētījumiem ar augsti efektīvo šķidruma hromatogrāfiju

6533b85efe1ef96bd12c016b

RESEARCH PRODUCT

Fludarabīna fosfāta injekciju piemaisījumu metodes izstrāde stabilitātes pētījumiem ar augsti efektīvo šķidruma hromatogrāfiju

Kaspars Kuprevičs

subject

description

Fludarabīna fosfāta injekciju piemaisījumu metodes izstrāde stabilitātes pētījumiem ar augsti efektīvo šķidruma hromatogrāfiju. Kaspars Kuprevičs, zinātniskie vadītāji: AS “Grindeks” Hromatogrāfijas laboratorijas vadītājs doktorants Juris Hmeļņickis un Dr. ķim., asoc. prof. Pēteris Mekšs. Bakalaura darbs, 52 lappuses, 28 attēli, 24 tabulas, 21 bibliogrāfiskie nosaukumi. Latviešu valodā. FLUDARABĪNS, AUGSTI EFEKTĪVĀ ŠĶIDRUMA HROMATOGRĀFIJA (AEŠH), PIEMAISĪJUMU NOTEIKŠANAS METODE, METODES VALIDĀCIJA. Bakalaura darbā tika izpētīta literatūra par fludarabīna fosfāta injekciju ķīmiskajām un fizikālajām īpašībām. Izpētīta informācija par hromatogrāfisko metožu izstrādi un validāciju. Bakalaura darbā tika izstrādāta un validēta analītiskā metode fludarabīna fosfātam piemaisījumu noteikšanai. Turpmāk šī metode tiks izmantota AS „Grindeks” ,lai noteiktu fludarabīna fosfāta piemaisījumus gatavai zāļu formai un produktam stabilitātes laikā.

year	journal	country	edition	language
2008-01-01

https://dspace.lu.lv/dspace/handle/7/22872

PEPhysical Sciences and Engineering
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