6533b85efe1ef96bd12c058c
RESEARCH PRODUCT
ChemInform Abstract: Synthesis of α-Fucosyl Glycosides and Disaccharides Using 4- Methoxybenzyl (Mpm) Protected Fucosyl Donors.
Horst KunzCarlo Unverzagtsubject
chemistry.chemical_classificationchemistry.chemical_compoundDouble bondChemistryStereochemistrymedicineGlycosideStereoselectivityGeneral MedicineChlorideFucosemedicine.drugdescription
The 4-methoxybenzyl (Mpm) group removable by selective oxidation was applied as a nonneighbouring-group-active protection of fucose hydroxy functions in the stereoselective synthesis of α-fucosides of acceptors containing double bonds sensitive to hydrogenation. With this aim, the synthesis of the α-fucosyl chloride (4) carrying the acidsensitive Mpm protection was elaborated.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-08-20 | ChemInform |