6533b85efe1ef96bd12c05f5

RESEARCH PRODUCT

pH-Dependent ligands as carriers in transport experiments

Ramón Martínez-máñezPablo GaviñaSalvador GilJuan P VillarroyaAna M. Costero

subject

chemistry.chemical_classificationCyclohexaneStereochemistryGeneral Chemical EngineeringPh dependentGeneral ChemistryCycloalkanechemistry.chemical_compoundMembraneHydrocarbonchemistryComputational chemistryPhase (matter)X-ray crystallographyCrown ether

description

Abstract Conformationally pH-regulated ligands have been used as carriers in transport experiments. The experiments were carried out through bulky membranes and the pH at the source phase and at the receiving phase were modified to study the ability of ligands to act as pH-regulated carriers. The influence of pH on transport efficiency seems to be related to its influence on conformational equilibrium. X-ray determination of one precursor compound has been useful for determining the stereochemistry of one of the carriers. To cite this article: A.M. Costero et al., C. R. Chimie 7 (2004).

https://doi.org/10.1016/j.crci.2003.08.013