6533b85efe1ef96bd12c064d
RESEARCH PRODUCT
Synthesis of (+)-Isoalantolactone and (+)-Isoalloalantolactone from (−)-Santonin
Begoña GarcíaLuz CardonaGonzalo BlayJosé R. PedroAngel Serranosubject
chemistry.chemical_classificationStereochemistryOrganic ChemistryRing (chemistry)SesquiterpeneBiochemistrychemistry.chemical_compoundchemistryDrug DiscoveryChemical conversionMoietyEnantiomerEnoneLactoneSantonindescription
Abstract This paper reports on the chemical conversion of (−)-santonin into (+)-isoalantolactone and (+)-isoalloalantolactone involving functionality transfer from C 6 to C 8 , refunctionalization of the ring A and the formation of the α-methylene-8 β,12-olide moiety.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-01-01 | Tetrahedron |