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6533b85efe1ef96bd12c0811

RESEARCH PRODUCT

New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration

T. OmataYuki KawaguchiVicente Herranz-pérezVicente Herranz-pérezNaoko KanekoNobuhiko OhnoNobuhiko OhnoKazunobu SawamotoKazunobu SawamotoHuy Bang NguyenHiromi SanoAtsushi NambuTruc Quynh ThaiJosé Manuel García-verdugoTakanobu Otsuka

subject

Male0301 basic medicineanimal structuresNeurogenesisBiologyLesionMice03 medical and health sciences0302 clinical medicineDevelopmental NeuroscienceNeuroblastCell MovementNeuroblast migrationmental disordersmedicineAnimalsRegenerationcardiovascular diseasesReceptors ImmunologicProgenitor cellcdc42 GTP-Binding ProteinResearch Articlesreproductive and urinary physiologyMice KnockoutNeuronsMultidisciplinaryRegeneration (biology)fungiNeurogenesisSciAdv r-articlesBrainActin cytoskeletonSlit-RoboActin Cytoskeleton030104 developmental biologynervous systemCellular NeuroscienceAstrocytesembryonic structuresIntercellular Signaling Peptides and ProteinsProtein Multimerizationmedicine.symptomNeurogliaNeurosciencepsychological phenomena and processes030217 neurology & neurosurgeryResearch ArticleProtein BindingSignal Transduction

description

Appropriate positioning of new neurons in the brain promotes post-stroke functional recovery.

yearjournalcountryeditionlanguage
2018-12-01Science Advances
https://doi.org/10.1126/sciadv.aav0618
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