6533b85efe1ef96bd12c0ddc

RESEARCH PRODUCT

Organotin(IV)derivatives neurotoxicity and their modulation by Baclofen

C. PrinzivalliM. AbbateGirolamo CasellaSalvatore CataldoTiziana FioreL. NagyClaudia PelleritoMichelangelo ScopellitiL. Pellerito

subject

Settore CHIM/03 - Chimica Generale E InorganicaOrganotin(IV) Baclofen Mossbauer FT-IR NMR

description

Several new diorganotin(IV) and triorganotin(IV) complexes with 4-amino-3- (4-chloro phenyl)]-butanoic acid ( = Baclofen) have been synthesized and their structure investigated both in the solid state and in solution phase through spectroscopic methods (FT-IR, Mössbauer, 1H and 13C NMR). According to experimental analytical data, the stoichiometry of the complexes has been proposed as R2SnBac2 and R3SnBac, respectively for diorganotin(IV) and triorganotin(IV) baclofen complexes. (Baclofen = HBac; R = Me, Bu, Ph).

http://hdl.handle.net/10447/35104