6533b85ffe1ef96bd12c1106

RESEARCH PRODUCT

Additional file 1: of MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease

Javier MilaraLucía Díaz-platasSonia ContrerasPilar RiberaInés RogerBeatriz BallesterPaula MonteroÁNgel CogolludoEsteban MorcilloJulio Cortijo

subject

respiratory systemrespiratory tract diseases

description

Figure S1. Acute cigarette smoke/ lipopolysaccharide lung inflammatory animal model showed resistance to dexamethasone improving lung resistance and bronchoalveolar inflammatory cell extravasation in Muc1 KO animals. Figure S2. IL-8 and IL-13 bronchoalveolar fluid content in Muc1 KO mice exposed to acute cigarette smoke/ lipopolysaccharide is resistant to dexamethasone. Figure S3. Inflammatory lung cell infiltration secondary to acute lipopolysaccharide/ cigarette smoke exposure is resistant to dexamethasone in MUC1 KO mice. (DOCX 1611 kb)

https://dx.doi.org/10.6084/m9.figshare.7369373