6533b85ffe1ef96bd12c1175
RESEARCH PRODUCT
Latent measles virus infection in Vero cells depending on a temperature-sensitive phenomenon.
A. ChiariniR. Di StefanoA. SinatraP. Ammatunasubject
biologyvirusesTemperatureGeneral MedicineHaplorhinibiology.organism_classificationVirus ReplicationVirologyVirusMicrobiologyCell LineMeasles virusIncubation temperatureCytopathogenic Effect ViralMeasles virusVirologyViral InterferenceVero cellAnimalsTemperature sensitiveAntigens Viraldescription
A latent infection by measles virus in a line of Vero cells could be maintained only at 37 degrees C. The conditions of temperature nonpermissiveness were associated with some block in virus production and/or release and with the establishment of an autointerference phenomenon. Reduction of the incubation temperature to 33.5 degrees C induced a rather rapid transition from the latent to a lytical infection with a recue of virus. The rescued virus exhibited a restricted capacity to grow at 37 degrees C.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1978-09-01 | Archives of virology |