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RESEARCH PRODUCT

The many roads to inflammatory bowel diseases.

Markus F. NeurathSusetta Finotto

subject

Gut inflammationInnate immune systemInterleukinsImmunologyToll-Like ReceptorsInflammatory Bowel DiseasesBiologyInflammatory Bowel DiseasesInterleukin-12Interleukin-23Immunity InnateInfectious DiseasesImmunityIntestinal inflammationImmunologyImmunology and AllergyAnimalsSignal Transduction

description

Two independent studies by Rakoff-Nahoum et al. (2006) and Uhlig et al. (2006) in this issue of Immunity have illuminated a unique pathogenic role of innate immunity via Toll-like receptor and interleukin-23 signaling, respectively, in intestinal inflammation. These data define new roads to gut inflammation and future avenues for therapy.

yearjournalcountryeditionlanguage
2006-08-01Immunity
10.1016/j.immuni.2006.08.005https://pubmed.ncbi.nlm.nih.gov/16919486