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RESEARCH PRODUCT
New options in assisted reproduction technology: the Cryotop method of oocyte vitrification
José BellverAna CoboSonia Fernandez PerezJuana CrespoJosé RemohíJavier DomingoAntonio Pellicersubject
AdultMaleReproductive Techniques Assistedmedia_common.quotation_subjectSingle geneBiologyPreimplantation genetic diagnosisPolymerase Chain ReactionEmbryo Culture TechniquesAndrologyEndometriumPregnancySurplus embryosEmbryo Culture TechniquemedicineHumansVitrificationPreimplantation Diagnosismedia_commonCryopreservationPregnancy OutcomeObstetrics and GynecologyOocyte cryopreservationOocyteHuntington Diseasemedicine.anatomical_structureReproductive MedicineOocytesFemaleReproductionPolycystic Ovary SyndromeDevelopmental Biologydescription
The Cryotop vitrification method has been shown to be a very useful tool for oocyte cryopreservation, giving excellent results regarding survival and clinical outcome. There are several clinical situations in which oocyte cryopreservation provides solutions that have not been available to date. This report describes three of these situations: (i) a low-responder patient who needed a single gene diagnosis due to the presence of a genetic disease; (ii) a patient undergoing endometrial bleeding on the day of oocyte retrieval who was also affected by a genetic disorder; and (iii) a patient who failed to become pregnant after the donation of vitrified oocytes and subsequently had the re-vitrified surplus embryos transferred. The resolution of these cases provides evidence of the enormous potential of the Cryotop method as a tool within assisted reproduction technology.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2008-07-12 | Reproductive BioMedicine Online |