6533b860fe1ef96bd12c2df4
RESEARCH PRODUCT
The Contribution of Microscopy to the Study of Alzheimer’s Disease, Amyloid Plaques and Aβ Fibrillogenesis
J. Robin Harrissubject
ChemistrylawConfocalMicroscopyP3 peptideBiophysicsFibrillogenesisSenile plaquesElectron microscopeFibrilBiochemistry of Alzheimer's diseaselaw.inventiondescription
A broad survey is presented in this chapter, dealing with the impact that microscopy has made to the study of Alzheimer’s disease, amyloid plaques and amyloid-β fibrillogenesis. This includes classical light microscopy and the modern immunolabelling and confocal microscopies, together with the contribution of transmission electron microscopy and atomic force microscopy. Whilst usefully standing alone, the individual microscopies often contribute most effectively when they are integrated with cellular, biophysical and molecular approaches.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-11-21 |