6533b860fe1ef96bd12c2fd1
RESEARCH PRODUCT
Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition
Rimbach RebeccaYamada YosukeSagayama HiroyukiAinslie Philip NAnderson Lene FAnderson Liam JArab LenoreBaddou IssaadBedu-addo KwekuBlaak Ellen EBlanc StephaneBonomi Alberto GBouten Carlijn V CBovet PascalBuchowski Maciej SButte Nancy FCamps Stefan G J AClose Graeme LCooper Jamie ADas Sai KrupaDugas Lara REkelund UlfEntringer SonjaForrester TerrenceFudge Barry WGoris Annelies HGurven MichaelHambly CatherineEl Hamdouchi AsmaaHoos Marije BHu SumeiJoonas NoorjehanJoosen Annemiek MKatzmarzyk PeterKempen Kitty PKimura MisakaKraus William EKushner Robert FLambert Estelle VLeonard William RLessan NaderMartin Corby KMedin Anine CMeijer Erwin PMorehen James CMorton James PNeuhouser Marian LNicklas Theresa AOjiambo Robert MPietiläinen Kirsi HPitsiladis Yannis PPlange-rhule JacobPlasqui GuyPrentice Ross LRabinovich Roberto ARacette Susan BRaichlen David ARavussin EricReynolds Rebecca MRoberts Susan BSchuit Albertine JSjödin Anders MStice EricUrlacher Samuel SValenti GiulioVan Etten Ludo MVan Mil Edgar AWells Jonathan C KWilson GeorgeWood Brian MYanovski JackYoshida TsukasaZhang XueyingMurphy-alford Alexia JLoechl Cornelia ULuke Amy HRood JenniferSchoeller Dale AWesterterp Klaas RWong William WSpeakman John RPontzer HermanSpeakman John Rsubject
Adipose Tissue/metabolismAdultMaleDatabases FactualBody Composition/physiologyScienceGeneral Physics and AstronomyWeight GainArticleGeneral Biochemistry Genetics and Molecular BiologyEnergy Metabolism/physiologyRC1200DatabasesClinical Research2.1 Biological and endogenous factorsHumansVDP::Medisinske Fag: 700ObesityLongitudinal StudiesAetiologyChildMetabolic and endocrineFactualWeight Gain/physiologyNutritionPediatricMultidisciplinaryWater/metabolismQWaterBayes TheoremGeneral ChemistryMiddle AgedRisk factorsAdipose TissueIsotope LabelingBody CompositionFemaleIAEA DLW Database ConsortiumEnergy Metabolismhuman activitiesdescription
Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, a critical variable in longitudinal studies of energy balance, is understudied. We examine repeated doubly labeled water (DLW) measurements of TEE in 348 adults and 47 children from the IAEA DLW Database (mean ± SD time interval: 1.9 ± 2.9 y) to assess repeatability of TEE, and to examine if TEE adjusted for age, sex, fat-free mass, and fat mass is associated with changes in weight or body composition. Here, we report that repeatability of TEE is high for adults, but not children. Bivariate Bayesian mixed models show no among or within-individual correlation between body composition (fat mass or percentage) and unadjusted TEE in adults. For adults aged 20–60 y (N = 267; time interval: 7.4 ± 12.2 weeks), increases in adjusted TEE are associated with weight gain but not with changes in body composition; results are similar for subjects with intervals >4 weeks (N = 53; 29.1 ± 12.8 weeks). This suggests low TEE is not a risk factor for, and high TEE is not protective against, weight or body fat gain over the time intervals tested.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-01-10 |