6533b860fe1ef96bd12c30e7

RESEARCH PRODUCT

New approach to condensed pyrid-2-ones

Eva M. BrunSalvador GilMargarita Parra

subject

ChemistryCarboxylic acidsUNESCO::QUÍMICAOrganic Chemistry:QUÍMICA::Química orgánica [UNESCO]HeterocyclesCombinatorial chemistry:QUÍMICA [UNESCO]Addition reactionslcsh:QD241-441lcsh:Organic chemistrySimple (abstract algebra)Computational chemistryNitrilesCarboxylic acids ; Nitriles ; Addition reactions ; Heterocycles ; Tandem reactionsTandem reactionsUNESCO::QUÍMICA::Química orgánica

description

We wish to report a simple procedure for the preparation of 5-substituted-thienopyridin-7-ones and 7-substituted-1,6-naphthyridin-5(6H)-ones, in good yields, from the dianions of 3-methylthiophene-2-carboxylic and 2-methylnicotinic acids on treatment with nitriles. Brun Sanchez, Eva Maria, Eva.M.Brun@uv.es ; Gil Grau, Salvador, Salvador.Gil@uv.es ; Parra Alvarez, Margarita, Margarita.Parra@uv.es

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