HSP90 in ageing progression and ageing related diseases

6533b860fe1ef96bd12c353d

RESEARCH PRODUCT

HSP90 in ageing progression and ageing related diseases

Walter Arancio Giuseppe Pizzolanti Carla Giordano

subject

HSP90 Ageing Settore BIO/11 - Biologia Molecolare

description

HSP90 activities decline during ageing. Noteworthy, HSP90 mediated retrotransposon silencing seems to have a key role in the maintenance of genome integrity. Furthermore, inhibition of HSP90 activities lead to cell senescence and apoptosis. Original bioinformatics analyses and literature data will be discussed in the light of the potential involvement of HSP90 in ageing progression and ageing related diseases.

year	journal	country	edition	language
2014-01-01

http://hdl.handle.net/10447/99426

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