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RESEARCH PRODUCT
A Longitudinal Study of Episodic and Semantic Autobiographical Memory in aMCI and Alzheimer’s Disease Patients
Iraida DelhomEncarna SatorresJuan C. MeléndezMireia AbellaElena RealAlfonso Pitarquesubject
Longitudinal studymedicine.medical_specialtyHealth Toxicology and MutagenesisMemory EpisodicDiseaseAudiologyNeuropsychological Tests050105 experimental psychologyArticle03 medical and health sciencesAutobiographical memory interview0302 clinical medicinemild cognitive impairmentAlzheimer DiseaseHealthy controlmedicineHumans0501 psychology and cognitive sciencesIn patientCognitive DysfunctionLongitudinal StudiesCognitive impairmentAgedAutobiographical memorybusiness.industry05 social sciencesautobiographical memoryPublic Health Environmental and Occupational HealthRSemanticsMedicinebusinessAlzheimer’s disease030217 neurology & neurosurgerydescription
Background: The main objective of this study was to analyze the evolution of autobiographical memory (both episodic and semantic) in patients with mild cognitive impairment, patients with Alzheimer’s disease, and a healthy control group. We compared these groups at two time points: first, at baseline, and in a follow-up after 18 months. Method: Twenty-six healthy older adults, 17 patients with mild amnestic cognitive impairment, and 16 patients with Alzheimer’s disease, matched on age and educational level, were evaluated at both time points with the Autobiographical Memory Interview. Results: The results showed significant longitudinal deterioration in episodic and semantic autobiographical memory in patients with mild cognitive impairment and in patients with Alzheimer’s disease, but not in healthy older adults. Conclusions: The deterioration of episodic and semantic autobiographical memory in AD is confirmed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-06-01 | International Journal of Environmental Research and Public Health |