6533b861fe1ef96bd12c430f
RESEARCH PRODUCT
Aging and longevity: An evolutionary approach
Calogero CarusoGiuseppina Candoresubject
media_common.quotation_subjectSufficient timeLongevityEpigeneticsBiologyNeurosciencemedia_commondescription
Abstract In the chapter, first of all, the definition of aging, longevity, and the various types of aging are discussed. Then, analyzing various theories of aging, it is recalled how evolution teaches us that there should be no genes selected to promote aging. Aging is not planned but derives from the accumulation of physical damage, due to limited investments in maintenance and repair as well as from the epigenetic changes. After sufficient time has passed, the increasing levels of these defects interfere with the performance of tissues and organs, resulting in a breakdown of self-organizing system and a reduced ability to adapt to the environment.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-01-01 |