6533b861fe1ef96bd12c4da9

RESEARCH PRODUCT

1-{3-[(7-Fluoro-9H-pyrimido[4,5-b]indol-4-yl)(methyl)amino]piperidin-1-yl}propan-1-one

Pierre KochStanislav AndreevDieter Schollmeyer

subject

crystal structurepyrimidoindoleCrystallographybiologykinase inhibitorStereochemistryHydrogen bondMeth-Crystal structurechemistry.chemical_compoundchemistryQD901-999biology.proteinGlycogen synthase

description

The title compound, C19H22FN5O, has been synthesized as an inhibitor of glycogen synthase kinase-3β. Two molecules interact via two N—H...N hydrogen bonds, forming centrosymmetric dimers.

https://doi.org/10.1107/s2414314621001590