6533b861fe1ef96bd12c57f1

RESEARCH PRODUCT

Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients.

Franchi CarlottaRossio RaffaellaArdoino IlariaNobili AlessandroMannucci Pier MannuccioPier Mannuccio MannucciNobili AlessandroAntonello PietrangeloFrancesco PerticoneGiuseppe LicataFrancesco VioliGino Roberto CorazzaCorrao SalvatoreAlessandra MarengoniFrancesco SalernoMatteo CesariMauro TettamantiLuca PasinaCarlotta FranchiCarlotta FranchiLaura CortesiMauro TettamantiGabriella MiglioMauro TettamantiLaura CortesiIlaria ArdoinoAlessio NovellaDomenico PriscoElena SilvestriGiacomo EmmiAlessandra BettiolCenci CaterinaGianni BioloMichela ZanettiMartina GuadagniMichele ZaccariMassimiliano ChiuchMichele ZaccariMassimo VanoliGiulia GrignaniEdoardo Alessandro PulixiMauro BernardiSilvia Li BassiLuca SantiGiacomo ZaccheriniGraziana LupattelliElmo MannarinoVanessa BianconiFrancesco PaciulloRiccardo AlcidiRanuccio NutiRoberto ValentiMartina RuvioSilvia CappelliAlberto PalazzuoliDomenico GirelliFabiana BustiGiacomo MarchiMario BarbagalloLigia DominguezFloriana CocitaVincenza BeneduceLidia PlancesSalvatore CorraoNatoli GiuseppeSalvatore MularoMassimo RaspantiFederica CavallaroMarco ZoliIlaria LazzariMattia BrunoriElisa FabbriDonatella MagalottiRaffaella ArnòFranco Laghi PasiniPier Leopoldo CapecchiGiuseppe PalascianoMaria Ester ModeoCarla Di GennaroMaria Domenica CappelliniDiletta MairaValeria Di StefanoGiovanna FabioSonia SeghezziMarta MancarellaMargherita Migone De AmicisGiacomo De LucaNatalia ScaramelliniMatteo CesariPaolo Dionigi RossiSarah DamantiMarta ClericiFederica ContiGiulia BoniniBarbara Brignolo OttoliniAntonio Di SabatinoEmanuela MiceliMarco Vincenzo LentiMartina PisatiCostanza Caccia DominioniGiovanni MurialdoAlessio MarraFederico CattaneoRoberto PontremoliValentina BeccatiGiulia NobiliMaria Beatrice SecchiDavide GhelfiLuigi AnastasioLucia SofiaMaria CarboneFrancesco CipolloneMaria Teresa GuagnanoEmanuele ValerianiIlaria RossiGerardo MancusoDaniela CalipariMosè BartoneGiuseppe DelitalaMaria BerriaChiara PesAlessandro DelitalaMaurizio MuscaritoliAlessio MolfinoEnrico PetrilloGiuseppe ZuccalàGabriella D’aurizioGiuseppe RomanelliAlessandra MarengoniAlberto ZucchelliFrancesca ManzoniAndrea VolpiniAntonio PicardiUmberto Vespasiani GentilucciPaolo GalloChiara Dell’untoGiorgio AnnoniMaurizio CorsiGiuseppe BellelliSara ZazzettaPaolo MazzolaHajnalka SzaboAlessandra BonfantiFranco ArturiElena SuccurroMariangela RubinoBruno TassoneGiorgio SestiMedicina InternaMaria Grazia SerraMaria Antonietta BleveLaura GasbarroneMaria Rosaria SajevaAntonio BrucatoSilvia GhidoniFabrizio FabrisIrene BertozziGiulia BogoniMaria Victoria RabuiniElisabetta CosiPaolo ScarinziAnnalisa AmabileElisabetta OmenettoTancredi PrandiniRoberto ManfrediniFabio FabbianBenedetta BoariAlfredo De GiorgiRuana TiseoRoberto De GiorgioGiuseppe PaolissoMaria Rosaria RizzoClaudio BorghiEnrico StrocchiEugenia IannielloMario SoldatiCarlo SabbàFrancesco Saverio VellaPatrizia SuppressaAndrea SchilardiFrancesca LoparcoGiovanni Michele De VincenzoAlessio ComitangeloEmanuele AmorusoLuigi FenoglioAndrea FalcettaChristian BraccoAnna L. FracanzaniSilvia FargionSilvia TiraboschiAnnalisa CespiatiGiovanna ObertiGiordano SigonFlora PeyvandiRaffaella RossioBarbara FerrariGiulia ColomboPasquale AgostiValter MonzaniValeria SavojardoChristian FolliGiuliana CerianiFrancesco SalernoGiada PalliniFranco DallegriLuciano OttonelloLuca LiberaleLara CaserzaKassem SalamNicola Lucio LiberatoTiziana TogninGiovanni Battista BianchiSabrina GiaquintoFrancesco PurrelloAntonino Di PinoSalvatore PiroRenzo RozziniLina FalangaElena SpazziniCamillo FerrandinaGiuseppe MontrucchioPaolo PetittiPaolo PeassoEdoardo FavaleCesare PolettoRaffaella SalmiPiergiorgio GaudenziFrancesco VioliLudovica PerriRaffaele LandolfiMassimo MontaltoAntonio MirijelloLuigina GuastiLuana CastiglioniAndrea MarescaAlessandro SquizzatoLeonardo CampiottiAlessandra GrossiMarco BertolottiChiara MussiGiulia LancellottiMaria Vittoria LibbraGiulia DondiElisa PellegriniLucia CarulliMatteo GalassiYasmine GrassiFrancesco PerticoneMaria PerticoneRosa BattagliaMarco FiliceRaffaele MaioVincenzo StanghelliniEugenio RuggeriSara Del VecchioAndrea SalviRoberto LeonardiGiampaolo DamianiWilliam CapeciArmando GabrielliMassimo MattioliGiuseppe Pio MartinoLorenzo BiondiPietro PettinariRiccardo GhioAnna Dal ColSalvatore MinisolaLuciano ColangeloMirella CilliGiancarlo LabbadiaAntonella AfeltraBenedetta MariglianoMaria Elena PipitaPietro CastellinoLuca ZanoliSamuele PignataroAlfio GennaroJulien BlancoValter SaraccoMarisa FogliatiCarlo BussolinoFrancesca MeteMiriam GinoAntonio CittadiniCarlo VigoritoMichele ArcopintoAndrea SalzanoEmanuele BobbioAlberto M. MarraSirico DomenicoGuido MoreoFrancesca GaspariniSilvia ProloGloria PinaAlberto BallestreroFabio FerrandoSergio BerraSimonetta DassiMaria Cristina NavaBruno GraziellaStefano BaldassarreSalvatore FragapaniGabriella GrudenGiorgio GalantiGabriele MascheriniCristian PetriLaura StefaniMargherita GirinoValeria PiccinelliFrancesco NassoVincenza GioffrèMaria PasqualeGiuseppe ScattolinSergio MartinelliMauro TurrinLeonardo SechiCristina CatenaGianluca ColussiNicola PassarielloLuca RinaldiFranco BertiGiuseppe FamularoPatrizia TarsitaniRoberto CastelloMichela PasinoGian Paolo CedaMarcello Giuseppe MaggioSimonetta MorgantiAndrea ArtoniStefano Del GiaccoDavide FirinuFrancesca LosaGiovanni PaolettiGiulia CostanzoGiuseppe MontaltoAnna LicataValentina MalerbaFilippo Alessandro MontaltoAntonino LascoGiorgio BasileAntonino CatalanoLorenzo MalatinoBenedetta StancanelliValentina TerranovaSalvatore Di MarcaRosario Di QuattroLara La MalfaRossella CarusoPatrizia MecocciCarmelinda RuggieroVirginia BoccardiTiziana MeschiFulvio LauretaniAndrea TicinesiAntonio NouvennePietro MinuzLuigi FondrieschiMario PirisiGian Paolo FraDaniele SolaMassimo PortaPiero RivaRoberto QuadriErica LarovereMarco NovelliGiorgio ScanziCaterina MengoliStella ProviniLaura RicevutiEmilio SimeoneRosa ScurtiFabio TollosoRoberto TarquiniAlice ValorianiSilvia DolentiGiulia VanniniAlberto TedeschiLucia TrottaRiccardo VolpiPietro BocchiAlessandro VignaliSergio HarariChiara LonatiMara CattaneoFederico Napoli

subject

Malemedicine.medical_specialtySocio-culturaleInappropriate Prescribing-Potentially inappropriate medication olderPractice Patternsdepression hospitalized patients drugselderlydrugsantidepressivi anzianoPolypharmacy | Inappropriate Prescribing | Medications PIMsantidepressant agent escitalopram paroxetineInternal MedicinemedicineHospital dischargeolderEscitalopramHumansLS4_4Medical prescriptionPractice Patterns Physicians'Depression (differential diagnoses)AgedPolypharmacySertralinePhysicians'antidepressantbusiness.industryTrazodonehospitalized patientsAntidepressive AgentsHospitalizationAcute Disease; Aged; Antidepressive Agents; Female; Humans; Inappropriate Prescribing; Italy; Male; Practice Patterns Physicians'; Hospitalizationantidepressants; elderlyItalyantidepressantsEmergency medicinedepressionAcute DiseasePolypharmacy Inappropriate Prescribing Medications PIMDeliriumFemalePotentially inappropriate medicationmedicine.symptombusinessmedicine.drug

description

Depression is often under-recognized in older patients, even if antidepressants (AD) are commonly prescribed, with a prevalence of use that increase with ageing [ 1 ]. Nevertheless, even if a diagnosis of depression is established, inappropriate treatment can occur [ 2 ]. Beers criteria are the most widely screening tools used to detect inappropriate prescription of drugs in people aged 65 years or more [ 3 ]. Since 2010, attempts to adapt the Beers' criteria have been made in Europe [ 4 , 5 ]. Tricyclic drugs are the ADs to be always avoided in the elderly, owing to their anticholinergic side effects, such as cognitive impairment, delirium, urinary retention and falls [ 3 ]. Selective serotonin reuptake inhibitors (SSRIs) should be used with caution because they can cause or exacerbate hyponatraemia [ 3 ]. To our knowledge no studies have been conducted on recent data collected in hospitalized older patients in order to assess the appropriateness of prescription of ADs. With this background, the objectives of this study were to investigate the prevalence of AD use and prescription appropriateness, according to the above-cited criteria, in a large cohort of older patients hospitalized in Italian internal medicine and geriatric wards from 2010 to 2017.

yearjournalcountryeditionlanguage
2019-01-01European journal of internal medicine
10.1016/j.ejim.2019.07.025https://pubmed.ncbi.nlm.nih.gov/31405773