AMPA Receptor Auxiliary Proteins of the CKAMP Family

6533b861fe1ef96bd12c59f1

RESEARCH PRODUCT

AMPA Receptor Auxiliary Proteins of the CKAMP Family

Jakob Von Engelhardt

subject

glutamate receptor hippocampus Gene Expression Review AMPA receptor Biology Synaptic Transmission Catalysis Cell Line lcsh:Chemistry Inorganic Chemistry Long term plasticity lateral geniculate nucleus Animals Humans Amino Acid Sequence Receptors AMPA AMPA receptor Physical and Theoretical Chemistry synaptic function Receptor lcsh:QH301-705.5 Molecular Biology Spectroscopy Neuronal Plasticity musculoskeletal neural and ocular physiology Organic Chemistry Glutamate receptor Geniculate Bodies General Medicine Subcellular localization long-term plasticity Computer Science Applications Cell biology Protein Transport Synaptic function lcsh:Biology (General)lcsh:QD1-999 nervous system auxiliary subunit Multigene Family Synapses Carrier Proteins Ion Channel Gating short-term plasticity Function (biology)Protein Binding

description

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are assembled of four core subunits and several additional interacting proteins. Cystine-knot AMPA receptor-modulating proteins (CKAMPs) constitute a family of four proteins that influence the trafficking, subcellular localization and function of AMPA receptors. The four CKAMP family members CKAMP39/shisa8, CKAMP44/shisa9, CKAMP52/shisa6 and CKAMP59/shisa7 differ in their expression profile and their modulatory influence on AMPA receptor function. In this review, I report about recent findings on the differential roles of CKAMP family members.

year	journal	country	edition	language
2019-03-01	International Journal of Molecular Sciences

https://doi.org/10.3390/ijms20061460

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