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RESEARCH PRODUCT

Membrane trafficking in immune singalin of plants

subject

description

Throughout their life, plants face with a vast diversity of beneficial and pathogenicmicrobes. Following microbe recognition, whatever the outcome of the interaction,intensive changes in membrane vesicle trafficking to and from the plasma membraneoccur. This allows plant cells to modify the spatio-temporal distribution and/or theactivity of membrane proteins, influencing their molecular dialogue with microbes. Asexample, a secreted protein from the oomycete Phytophthora cryptogea elicitsdefense reactions against pathogens by a transcriptional reprogramming and celldeath of tobacco cells. In early steps, the microbe protein stimulates clathrin-mediated endocytosis and plasma membrane reorganization. These membraneprocesses are dependent on reactive oxygen species generated by the NADPHoxidase D. Interrelations between signaling events and membrane dynamics, whichcan ultimately trigger immune responses, will be discussed.