6533b862fe1ef96bd12c603e

RESEARCH PRODUCT

Haemophagocytic syndrome and rickettsial diseases. A new case and systematic review of the literature

Antonio CascioS GiordanoP DonesS VeneziaChiara IariaO. Ziino

subject

Haemophagocytic

description

Haemophagocytic lymphohistiocytosis is a rare but potentially fatal disease resulting from dysregulated activation and proliferation of lymphocytes. We present a case of haemophagocytic syndrome occurring in a 5-year-old Italian boy as a complication of Mediterranean spotted fever. The characteristics of this case have been analysed and contextualized among those of another 15 cases of haemophagocytic syndrome associated with rickettsial diseases found through a systematic review of the international literature.

10.1099/jmm.0.025833-0http://hdl.handle.net/10447/379928