6533b862fe1ef96bd12c611b

RESEARCH PRODUCT

Complex formation of hypoxanthine and 6-mercaptopurine with Cd(II) ion

Lucia SotoJuan C. GordoFrancisco J. GordoJoaquín BorrásL. Perelló

subject

Thermogravimetric analysisChemistryComplex formationInfrared spectroscopyGeneral ChemistryMercaptopurineIonchemistry.chemical_compoundStability constants of complexesIonic strengthmedicineHypoxanthinemedicine.drugNuclear chemistry

description

Reaction of Cd(II) ion with hypoxanthine (H2 Y) and with 6-mercaptopurine (H2 MP) in dioxane-water (50%) leads to the formation of CdY·2H2O and Cd(HMP)2·2H2O, respectively. In methanolic medium Cd(II) and H2 MP give Cd(MP)·H2O. These compounds have been characterized by chemical analysis, IR spectra and thermogravimetric analysis. The stability constant of CdY complex at 25±0.1 °C and 1M ionic strength with NaClO4 in dioxane-water medium is log β=10.25±0.05.

https://doi.org/10.1007/bf00816334