A breakdown in macromolecular synthesis preceding differentiation in Streptomyces coelicolor A3(2)

6533b862fe1ef96bd12c6367

RESEARCH PRODUCT

A breakdown in macromolecular synthesis preceding differentiation in Streptomyces coelicolor A3(2)

M. Sollazzo Rosa Passantino R. Billetta C. Granozzi Anna Maria Puglia

subject

DNA Replication DNA Bacterial biology Streptomycetaceae Cell Cycle Streptomyces coelicolor biology.organism_classification Microbiology Streptomyces Kinetics RNA Bacterial chemistry.chemical_compound Biochemistry Biosynthesis chemistry Protein Biosynthesis Nucleic acid Actinomycetales Bacteria Mycelium Macromolecule

description

Summary: A transitory cessation of growth was recorded in Streptomyces coelicolor A3(2) at the end of vegetative mycelium formation on solid medium. In the same phase a striking reduction in protein and nucleic acid synthesis was detected. Growth and macromolecular synthesis resumed, nearly reaching the original values, when morphological differentiation occurred. It is concluded that a physiological stress occurs within the bacterial population just before the onset of the morphological differentiation.

year	journal	country	edition	language
1990-04-01	Journal of General Microbiology

https://doi.org/10.1099/00221287-136-4-713

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