6533b862fe1ef96bd12c6a8b
RESEARCH PRODUCT
Evaluation of Aspects Controlling Crystallization of Nitrofurantoin
Agris BerzinsAija Trimdalesubject
Chemical engineeringMechanics of MaterialslawNitrofurantoinChemistryMechanical EngineeringmedicineGeneral Materials ScienceCrystallizationlaw.inventionmedicine.drugdescription
Nitrofurantoin was crystallized from multiple mixtures of water and organic solvents with and without additives to try to find and identify factors affecting phase obtained in crystallization and provide possible information on crystallization control. Obtained crystals were identified with powder X-ray diffractometry. Crystallization control possibilities were evaluated by using polymer additives and crystallization additives, by also using quantum chemical calculations to investigate the association of nitrofurantoin and additive molecules and calculate Gibbs energy of association.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-04-01 | Key Engineering Materials |