Glomerulosclerosis nodular diabética sin diabetes mellitus conocida previamente

6533b862fe1ef96bd12c6b06

RESEARCH PRODUCT

Glomerulosclerosis nodular diabética sin diabetes mellitus conocida previamente

José Luis Górriz Teruel Antonio Galán Serrano Carlos Sánchez Juan Belén Serra Sanchis Juan Carlos Ferrer García Lidia Castellano Roig

subject

Endocrinology Endocrinology Diabetes and Metabolism

description

La nefropatia es una de las complicaciones cronicas de la diabetes mellitus relacionadas con un incremento de la morbimortalidad en la poblacion afectada. Puede detectarse tras varios anos de evolucion de la enfermedad en el caso de la diabetes tipo 1, al poco tiempo del diagnostico en la diabetes tipo 2 e incluso al inicio de esta, y es muy infrecuente sin diabetes mellitus previamente conocida. Presentamos 2 casos de nefropatia diabetica en pacientes sin historia previa de diabetes mellitus. Uno de ellos fue diagnosticado posteriormente de intolerancia a los hidratos de carbono. En el otro, el estudio del metabolismo hidrocarbonado fue normal. Se revisa la bibliografia y se discute sobre los mecanismos geneticos y ambientales implicados en el desarrollo de la intolerancia. Se discute tambien la importancia de incluir la nefropatia diabetica en el diagnostico diferencial de la glomerulosclerosis nodular, incluso en casos sin diabetes mellitus previamente conocida.

year	journal	country	edition	language
2006-12-01	Endocrinología y Nutrición

https://doi.org/10.1016/s1575-0922(06)71159-7

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