6533b862fe1ef96bd12c6b6b
RESEARCH PRODUCT
Chromatographic Separation of Cresol Isomers by a β‐Cyclodextrin: Application for the Determination of Volatile Phenols in Alcoholic Beverages
R. Marín-saezM. Llobat-estellésM. Escarti‐carrascoAdela R. Mauri-aucejosubject
Detection limitchemistry.chemical_classificationChromatographyCyclodextrinElutionBiochemistry (medical)Clinical BiochemistryFluorescence spectrometryCresolBiochemistryAnalytical ChemistryMatrix (chemical analysis)chemistry.chemical_compoundchemistryReagentparasitic diseasesElectrochemistrymedicineOrganic chemistryPhenolsSpectroscopymedicine.drugdescription
Abstract The chromatographic separation of o‐cresol, m‐cresol, and p‐cresol by using β‐cyclodextrin as a chiral reagent has been studied. Conditions for the chromatographic separation of these isomers by using the cyclodextrin in the mobile phase or bonded in the stationary phase were optimized, and both procedures provided good results for the resolution of the chromatographic peaks. The use of fluorimetric detection (λexc 275 nm λem 300 nm) allows detection and quantification limits of the µg/L for eight studied phenols by using both procedures. The determination of volatile phenols in alcoholic beverages must be carried out using the cyclodextrin in the mobile phase because of the co‐elution of phenol and ethylguaiacol with other compounds of some studied matrix.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-01-01 | Analytical Letters |