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RESEARCH PRODUCT
Similarities and Differences: Signaling Mechanisms Induced by Contact Sensitizers
Detlef Beckersubject
business.industrymedia_common.quotation_subjectmedicine.medical_treatmentCell BiologyDermatologyBiochemistryPresentationAntigenImmunologymedicineAntigen-presenting cellbusinessMolecular BiologyAdjuvantmedia_commondescription
Keeping in mind our detailed knowledge on the uptake, processing and presentation of protein antigens, little is known on the handling of contact sensitizers by antigen presenting cells (APC). Contact sensitizers have the unique capacity to activate APC without further adjuvant signals. Although numerous studies have addressed the cellular and functional changes during this process, little is known about the underlying signaling mechanisms.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-03-01 | Journal of Investigative Dermatology |