6533b863fe1ef96bd12c7c01

RESEARCH PRODUCT

Isolation and characterization of Citrus limon L. derived nanovesicles: potential use as antineoplastic agent

Stefania RaimondoFlores NaselliSimona FontanaFrancesca MonteleoneAlessia Lo DicoLaura SaievaGiovanni ZitoAnna Maria Flugy Pape'Mauro MannoMaria Antonietta Di BellaGiacomo De LeoRiccardo Alessandro

subject

nanovesicles citrus limon

description

We isolated and characterized nanovesicles from edible Citrus limon with size and composition similar to mammalian-derived exosomes. Furthermore we show an in vitro and in vivo anti-proliferative and pro-apoptotic effect of these vesicles. This study opens to the possibility of using this natural plant-derived nanovesicles as antineoplastic agents.

10.3402/jev.v4.27783http://hdl.handle.net/10447/132213