FOKI AND BSMI VITAMIN D RECEPTOR GENE POLYMORPHISMS, ARE THEY ASSOCIATED WITH INTIMA MEDIA THICKNESS IN ESSENTIAL HYPERTENSIVE INDIVIDUALS

6533b86cfe1ef96bd12c7e46

RESEARCH PRODUCT

FOKI AND BSMI VITAMIN D RECEPTOR GENE POLYMORPHISMS, ARE THEY ASSOCIATED WITH INTIMA MEDIA THICKNESS IN ESSENTIAL HYPERTENSIVE INDIVIDUALS

Laura Guarino Giulio Geraci R. Arsena Francesco Vaccaro Marco Guarneri Concetta Scazzone Giuseppe Mule'Santina Cottone

subject

ESSENTIAL HYPERTENSION.VITAMIN D VITAMIN D RECEPTOR GENE POLYMORPHISMS CAROTID ATHEROSCLEROSIS

description

Objective: Analyzing 25hydroxyvitaminD (25[OH]D) serum levels and common carotid intimamedia thickness (IMT) relationship, and evaluating the association of FokI and BsmI vitamin D receptor (VDR) gene polymorphisms with IMT in essential hypertensive patients were our study aims. Design and method: We enrolled seventyone essential hypertensive patients, 18–75 years old. Patients underwent clinical blood pressure (BP) measurement, 24 hour ambulatory blood pressure monitoring, routine blood test, 25[OH]D assay and common carotid IMT evaluation. FokI and BsmIVDRpolymorphisms were analyzed by polymerase chain reactionrestriction fragment length polymorphism (PCRRFLP).

year	journal	country	edition	language
2015-01-01

https://iris.unipa.it/handle/10447/139637

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