6533b86cfe1ef96bd12c7ed5

RESEARCH PRODUCT

In vivo angiotensin I-converting enzyme inhibition by long-term intake of antihypertensive lactoferrin hydrolysate in spontaneously hypertensive rats

Paloma ManzanaresRicardo Fernández-musolesEnrique AlborchMaría C. BurgueteJuan B. Salom

subject

medicine.medical_specialtybiologyChemistryLactoferrinCaptoprilHydrolysateSpontaneously hypertensive ratEndocrinologyMechanism of actionOral administrationIn vivoInternal medicineRenin–angiotensin systemmedicinebiology.proteinmedicine.symptomFood Sciencemedicine.drug

description

Abstract We evaluated the effect of the long-term intake of a bovine lactoferrin hydrolysate enriched in low molecular weight peptides (LFH  in vivo mechanism of action. Male spontaneously hypertensive rats received tap water (negative control), captopril (positive control, 76 mg/kg/day), LFH  in vivo mechanism for the antihypertensive effect of long-term oral administration of LFH

https://doi.org/10.1016/j.foodres.2013.07.063