Radioactively labelled epoxides. Part III. Tritium labelled steroid 16α, 17α-epoxides

6533b86cfe1ef96bd12c7f9f

RESEARCH PRODUCT

Radioactively labelled epoxides. Part III. Tritium labelled steroid 16α, 17α-epoxides

subject

Chromatography Tritiated water Chemistry medicine.medical_treatment Organic Chemistry Radiochemistry Biochemistry Analytical Chemistry Steroid Part iii chemistry.chemical_compound Drug Discovery medicine Radiology Nuclear Medicine and imaging Tritium Spectroscopy

description

Tritium labelled (17-3H) 16α, 17α-epoxy-androst-4-en-3-one and 16α, 17α-epoxy-estra-1,3,5(10)-trien-3-ol have been prepared on a large scale (200-300 mg amounts) with efficient (i.e. activity of product exactly predictable) introduction of label. The preparative method is very inexpensive, since the tritium derives from tritiated water, the steroid starting materials are readily available, and high yields are obtained in all steps.

year	journal	country	edition	language
1980-09-01	Journal of Labelled Compounds and Radiopharmaceuticals

https://doi.org/10.1002/jlcr.2580170507

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