6533b86cfe1ef96bd12c80f6
RESEARCH PRODUCT
Nanomaterial-based cocaine aptasensors.
Khalil AbnousMiguel De La GuardiaJafar Ezzati Nazhad DolatabadiAhad MokhtarzadehMohammad Ramezanisubject
OligonucleotideComputer scienceAptamerBiomedical EngineeringBiophysicsDNA Single-StrandedNanotechnologyGeneral MedicineBiosensing TechniquesElectrochemical TechniquesAptamers NucleotideRapid detectionQuantitative determinationFluorescenceCocaineNanosensorElectrochemistryMolecular targetsHumansColorimetryBiosensorBiotechnologydescription
Up to now, many different methods have been developed for detection of cocaine, but most of these methods are usually time-consuming, tedious and require special or expensive equipment. Therefore, the development of simple, sensitive and rapid detection methods is necessary. In the last decade, aptamers have been used as a new biosensor platform for detection of cocaine in different samples. Aptamers are artificial single-stranded DNA or RNA oligonucleotides capable of binding to specific molecular targets with high affinity and if integrated to nanomaterials, it may lead in precise methods for cocaine detection in the common laboratories. In this review, recent advances and applications of aptamer-based biosensors and nanobiosensors, have been updated, paying attention to the use of fluorescence, colorimetric and electrochemical techniques for the detection and quantitative determination of cocaine.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-06-01 | Biosensorsbioelectronics |