6533b86cfe1ef96bd12c8136

RESEARCH PRODUCT

Extremely potent antifeedant neo-clerodane derivatives of scutecyprol A

Antonella MaggioMonique S. J. SimmondsMaurizio BrunoSergio RosselliFranco Piozzi

subject

InsecticidesbiologyScutellaria sieberiScutalbin CStereochemistryScutellariaGeneral ChemistryhalohydrinSpodoptera littoralisSpodopterabiology.organism_classificationantifeedant activityDiterpenes ClerodaneLepidoptera genitaliachemistry.chemical_compoundchemistryAcetoneNoctuidaeAnimalsscutecyprol ASettore BIO/15 - Biologia FarmaceuticaScutellaria sieberiGeneral Agricultural and Biological SciencesSpodoptera littoralis

description

Two known neo-clerodane diterpenoids, scutecyprol A (1) and scutalbin C (2), have been isolated from the acetone extract of the aerial parts of Scutellaria sieberi. The antifeedant activity of scutecyprol A (1), of its 15-oxo derivative (3), and of several halohydrins (4-9), synthesized starting from compounds 1 and 3, against Spodoptera littoralis have been determined and structure-antifeedant relationships are discussed.

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