6533b86cfe1ef96bd12c8a87
RESEARCH PRODUCT
Recent Advances in Affinity MOF-Based Sorbents with Sample Preparation Purposes
Héctor Martínez Pérez-cejuelaErnesto F. Simó-alfonsoJosé Manuel Herrero-martínezsubject
ProteomicsPolymersAptamerCarbohydratesaptamersPharmaceutical ScienceBiocompatible MaterialsNanotechnologyReviewLigandsbiomoleculesAnalytical ChemistryPhysical Phenomenalcsh:QD241-441metal–organic frameworkslcsh:Organic chemistryBiomimeticsDrug DiscoveryHumansantibodiessolid-phase extractionSample preparationPhysical and Theoretical Chemistrysample treatmentMetal-Organic Frameworkschemistry.chemical_classificationamino acidsBiomoleculeSolid Phase ExtractionOrganic ChemistryfungiProteinsmolecular imprinted polymersnucleobasesChemistrychemistryChemistry (miscellaneous)Microscopy Electron ScanningMolecular MedicineMetal-organic frameworkAdsorptionProtein Bindingdescription
This review summarizes the recent advances concerning metal–organic frameworks (MOFs) modified with several biomolecules (e.g., amino acids, nucleobases, proteins, antibodies, aptamers, etc.) as ligands to prepare affinity-based sorbents for application in the sample preparation field. The preparation and incorporation strategies of these MOF-based affinity materials were described. Additionally, the different types of ligands that can be employed for the synthesis of these biocomposites and their application as sorbents for the selective extraction of molecules and clean-up of complex real samples is reported. The most important features of the developed biocomposites will be discussed throughout the text in different sections, and several examples will be also commented on in detail.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-09-01 | Molecules |