6533b86cfe1ef96bd12c8aeb

RESEARCH PRODUCT

Thermolysis of 3-(carbazol-3-yl)-2-azidopropenoates

Elena Zaballos-garcíaJosé Sepúlveda-arquesM. Luisa TestaEugenia Gonzalez-rosendeR. Alan JonesLourdes Rodriguez-salvador

subject

chemistry.chemical_compoundchemistryCarbazoleOrganic ChemistryDrug DiscoveryThermal decompositionOrganic chemistryBiochemistryMedicinal chemistryDerivative (chemistry)

description

Abstract Thermal cyclisation of 2-azido-3-(carbazol-3-yl)propenoic esters produces the 1,6-dihydropyrrolo[3,2- c ]carbazole and not the 1,9-dihydropyrrolo[2,3- b ]carbazole whereas, in the case of the 4-methylcarbazolyl derivative, the 1,9-dihydropyrrolo[2,3- b ]-carbazole is formed in preference to the alternative pyrido[4,3- c ]carbazole.

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