6533b86cfe1ef96bd12c8b04

RESEARCH PRODUCT

Wheat consumption leads to immune activation and symptom worsening in patients with familial mediterranean fever : a pilot randomized trial

Antonio CarroccioPasquale MansuetoMaurizio SoresiFrancesca FayerDiana Di LibertoErika MonguzziMarianna Lo PizzoFrancesco La BlascaGirolamo GeraciAlice PecoraroFrancesco DieliDetlef Schuppan

subject

AdultMalenon-celiac wheat sensitivityCD14 lymphocytesLipopolysaccharide Receptors610 Medizinlcsh:TX341-641Wheat HypersensitivityMonocytesArticleDouble-Blind MethodAIDAI score610 Medical sciencesHumansTriticumCross-Over Studiesinterleukin-1betaTumor Necrosis Factor-alphaCD14 lymphocytefood and beveragesFamilial Mediterranean FeverDisease ProgressionFemaletumor necrosis factor-αlcsh:Nutrition. Foods and food supplyamylase trypsin inhibitor

description

We have identified a clinical association between self-reported non-celiac wheat sensitivity (NCWS) and Familial Mediterranean Fever (FMF). Objectives: A) To determine whether a 2-week double-blind placebo-controlled (DBPC) cross-over wheat vs. rice challenge exacerbates the clinical manifestations of FMF

https://dx.doi.org/10.25358/openscience-5228